HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0007165 - signal transduction GO:0019904 - protein domain specific binding and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1657
+	Hs
		809256 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		IQGA1_HUMAN (1-1657): 0: 1732: 100.00
+	Hs
		910133 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NGAP_HUMAN (666-1452): 7.71e-126: 425: 12.89
+	Hs
		647363 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NGAP_HUMAN (666-1452): 7.71e-126: 425: 12.89
+	Hs
		909664 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DAB2P_HUMAN (734-1450): 6.67e-122: 415: 12.45
+	Hs
		909774 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		RASL3_HUMAN (743-1570): 2.58e-122: 412: 12.97
+	Hs
		646987 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DAB2P_HUMAN (734-1450): 6.67e-122: 415: 12.45
+	Hs
		927150 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		DAB2P_HUMAN (734-1450): 6.67e-122: 415: 12.45
+	Hs
		927262 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		RASL3_HUMAN (743-1570): 2.58e-122: 412: 12.97
+	Hs
		909931 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SYGP1_HUMAN (635-1477): 1.49e-108: 380: 12.26
+	Mm
		99940 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		SYGP1_MOUSE (635-1477): 1.84e-107: 376: 11.98
+	Hs
		647202 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SYGP1_HUMAN (635-1477): 1.49e-108: 380: 12.26
+	Hs
		927424 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SYGP1_HUMAN (635-1477): 1.49e-108: 380: 12.26
+	Mm
		99950 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		SYGP1_MOUSE (635-1477): 1.84e-107: 376: 11.98
+	Hs
		909576 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		GAPD1_HUMAN (867-1481): 1.38e-83: 305: 15.18
+	Hs
		927058 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		GAPD1_HUMAN (867-1481): 1.38e-83: 305: 15.18
+	Hs
		598455 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NF1_HUMAN (1002-1317): 3.97e-57: 221: 21.60
+	Mm
		910233 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NF1_MOUSE (1002-1317): 5.38e-57: 221: 21.89
+	Mm
		926782 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		NF1_MOUSE (1002-1317): 5.38e-57: 221: 21.89
+	Hs
		598427 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NF1_HUMAN (1002-1317): 3.97e-57: 221: 21.60
+	Hs
		598458 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		NF1_HUMAN (1002-1317): 3.97e-57: 221: 21.60