HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: GSK3A (P49840)
Glycogen synthase kinase-3 alpha (GSK-3 alpha) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3A) (EC 2.7.11.1)
Gene: GSK3A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	27684187, 36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 483
+	Hs
		835306 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00
+	Hs
		683210 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00
+	Hs
		625306 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03
+	Hs
		625130 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03
+	Hs
		625334 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03
+	Hs
		835641 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41
+	Hs
		683211 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		GSK3B_HUMAN (65-471): 1.58e-145: 424: 76.41
+	Bt
		61645 1433Z_BOVIN (1-245): 1.75e-141: 397: 79.59		A6H7A9_BOVIN (65-473): 2.45e-142: 417: 73.46
+	Hs
		909447 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50
+	Hs
		646799 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50
+	Hs
		683268 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50
+	Hs
		683909 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00
+	Hs
		835337 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00
+	Hs
		835301 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		GSK3A_HUMAN (16-483): 7.48e-155: 450: 100.00
+	Hs
		625383 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03
+	Hs
		625296 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		CDK2_HUMAN (116-413): 1.52e-147: 425: 32.03
+	Hs
		683964 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50
+	Hs
		960082 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		CDK3_HUMAN (116-425): 2.95e-138: 401: 30.50