HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PPP5 (P53041)
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT)
Gene: PPP5C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28330616
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 499
+	Hs
		683220 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PPP5_HUMAN (1-499): 0: 575: 100.00
+	Hs
		909432 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PP2AA_HUMAN (190-481): 5.28e-167: 475: 40.88
+	Mm
		915319 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PP2AB_MOUSE (182-485): 6.26e-163: 465: 38.69
+	Mm
		906225 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		PP1A_MOUSE (200-479): 2.47e-154: 444: 38.79
+	Hs
		905812 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Mm
		906229 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PP1A_MOUSE (200-479): 2.47e-154: 444: 38.79
+	Mm
		926530 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PP1G_MOUSE (196-488): 1.32e-154: 444: 36.88
+	Hs
		646689 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88
+	Bt
		898865 1433Z_BOVIN (1-245): 1.75e-141: 397: 79.59		PP1G_BOVIN (196-488): 1.32e-154: 444: 36.88
+	Mm
		906231 1433T_MOUSE (1-245): 2.96e-141: 397: 99.59		PP1A_MOUSE (200-479): 2.47e-154: 444: 38.79
+	Hs
		683174 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PP1G_HUMAN (196-488): 1.79e-154: 444: 36.88
+	Hs
		905846 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Mm
		905328 1433G_MOUSE (1-242): 5.48e-105: 305: 70.33		PP1A_MOUSE (200-479): 2.47e-154: 444: 38.79
+	Hs
		904418 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		PP1A_HUMAN (200-479): 5.19e-154: 443: 38.79
+	Hs
		156602 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PPE1_HUMAN (156-487): 8.16e-68: 231: 34.12