HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: ACTG (P63261)
Actin, cytoplasmic 2 (EC 3.6.4.-) (Gamma-actin) [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]
Gene: ACTG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20618440
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0016020 - membrane GO:0045202 - synapse and 1 others more... GO:0070062 - extracellular exosome
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 375
+	Mm
		935546 1433F_MOUSE (2-242): 4.62e-106: 308: 71.43		ACTBL_MOUSE (1-375): 0: 741: 92.27
+	Hs
		891665 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Mm
		926767 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		ACTG_MOUSE (1-375): 0: 604: 100.00
+	Hs
		646763 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		891673 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ACTB_HUMAN (1-375): 0: 604: 98.93
+	Hs
		909433 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		926908 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Mm
		926769 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		ACTS_MOUSE (2-375): 0: 594: 93.85
+	Hs
		646777 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		926910 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		915357 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		683256 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		ACTC_HUMAN (2-375): 0: 595: 94.39
+	Hs
		683952 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ACTG_HUMAN (1-375): 0: 604: 100.00
+	Hs
		683941 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ACTA_HUMAN (2-375): 0: 594: 94.39
+	Hs
		683954 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ACTS_HUMAN (2-375): 0: 594: 93.85
+	Hs
		904433 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		ACTC_HUMAN (2-375): 0: 595: 94.39