HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: CDK17 (Q00537)
Cyclin-dependent kinase 17 (EC 2.7.11.22) (Cell division protein kinase 17) (PCTAIRE-motif protein kinase 2) (Serine/threonine-protein kinase PCTAIRE-2)
Gene: CDK17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	33961781, 36931259, 15161933, 28514442
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 523
+	Hs
		909449 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK17_HUMAN (1-523): 0: 544: 100.00
+	Hs
		926925 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CDK17_HUMAN (1-523): 0: 544: 100.00
+	Hs
		909448 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		625306 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35
+	Hs
		646800 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		926924 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CDK16_HUMAN (1-513): 1.11e-158: 462: 69.20
+	Hs
		625130 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35
+	Hs
		625334 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CDK2_HUMAN (189-484): 1.93e-160: 459: 52.35
+	Hs
		909447 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK3_HUMAN (189-492): 3.96e-152: 438: 50.98
+	Hs
		646799 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CDK3_HUMAN (189-492): 3.96e-152: 438: 50.98
+	Hs
		909472 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK18_HUMAN (54-522): 1.08e-145: 428: 66.31
+	Hs
		646826 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CDK18_HUMAN (54-522): 1.08e-145: 428: 66.31
+	Hs
		926960 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CDK18_HUMAN (54-522): 1.08e-145: 428: 66.31
+	At
		965298 14332_ARATH (3-243): 8.65e-144: 404: 61.22		MPK7_ARATH (161-519): 2.65e-138: 405: 30.06
+	Dm
		955007 1433E_DROME (2-242): 6.77e-143: 401: 65.02		Q7KM03_DROME (108-506): 5.01e-134: 400: 50.97
+	Dm
		955011 1433E_DROME (2-242): 6.77e-143: 401: 65.02		Q94888_DROME (87-506): 2.71e-134: 400: 48.50
+	Hs
		300632 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89
+	Hs
		300626 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89
+	Hs
		300633 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89
+	Hs
		300628 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		CDK14_HUMAN (164-520): 5.9e-131: 390: 53.89