HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: ROR2 (Q01974)
Tyrosine-protein kinase transmembrane receptor ROR2 (EC 2.7.10.1) (Neurotrophic tyrosine kinase, receptor-related 2)
Gene: ROR2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 943
+	Hs
		926941 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ROR2_HUMAN (1-943): 0: 840: 100.00
+	Hs
		169169 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MUSK_HUMAN (5-756): 8.41e-178: 539: 24.13
+	Hs
		601493 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		FGFR2_HUMAN (18-804): 9.32e-172: 522: 19.65
+	Hs
		674386 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		UFO_HUMAN (28-837): 6.67e-148: 462: 19.23
+	At
		965320 14332_ARATH (3-243): 8.65e-144: 404: 61.22		BAK1_ARATH (223-798): 2.14e-148: 454: 13.77
+	At
		1277300 14337_ARATH (2-243): 2.78e-142: 400: 60.32		SERK1_ARATH (182-794): 3.64e-149: 457: 14.53
+	Hs
		909494 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MERTK_HUMAN (17-898): 2.29e-139: 443: 16.32
+	Hs
		909589 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ERBB4_HUMAN (139-924): 3.66e-135: 439: 20.89
+	Hs
		646846 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MERTK_HUMAN (17-898): 2.29e-139: 443: 16.32
+	Hs
		909605 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NTRK3_HUMAN (259-755): 4.11e-127: 406: 28.91
+	Hs
		909560 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		FAK2_HUMAN (429-864): 6.44e-113: 372: 29.00
+	Hs
		384604 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NTRK1_HUMAN (478-748): 6.27e-66: 238: 43.91
+	Hs
		384306 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NTRK1_HUMAN (478-748): 6.27e-66: 238: 43.91
+	Hs
		384623 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		NTRK1_HUMAN (478-748): 6.27e-66: 238: 43.91
+	Hs
		384357 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		NTRK1_HUMAN (478-748): 6.27e-66: 238: 43.91
+	Hs
		435597 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		IGF1R_HUMAN (467-747): 1.28e-51: 199: 37.68
+	Hs
		435542 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		IGF1R_HUMAN (467-747): 1.28e-51: 199: 37.68
+	Hs
		435604 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		IGF1R_HUMAN (467-747): 1.28e-51: 199: 37.68
+	Hs
		411315 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		INSR_HUMAN (467-747): 2.53e-53: 204: 39.15
+	Hs
		435553 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		IGF1R_HUMAN (467-747): 1.28e-51: 199: 37.68