HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: KPCT (Q04759)
Protein kinase C theta type (EC 2.7.11.13) (nPKC-theta)
Gene: PRKCQ

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	8816492
Identification Methods	affinity chromatography technology, far western blotting
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 706
+	Hs
		926957 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KPCD_HUMAN (1-705): 0: 769: 61.99
+	Hs
		683287 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KPCD_HUMAN (1-705): 0: 769: 61.99
+	Hs
		909458 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KPCE_HUMAN (21-696): 0: 693: 40.99
+	Hs
		646812 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KPCE_HUMAN (21-696): 0: 693: 40.99
+	Hs
		926942 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KPCE_HUMAN (21-696): 0: 693: 40.99
+	Hs
		683276 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KPCE_HUMAN (21-696): 0: 693: 40.99
+	Hs
		783970 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KPCI_HUMAN (57-699): 0: 540: 28.72
+	Hs
		646701 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KPCI_HUMAN (57-699): 0: 540: 28.72
+	Hs
		783973 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KPCI_HUMAN (57-699): 0: 540: 28.72
+	Hs
		566293 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KPCA_HUMAN (129-701): 0: 534: 36.64
+	Hs
		566348 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KPCA_HUMAN (129-701): 0: 534: 36.64
+	Hs
		683182 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KPCI_HUMAN (57-699): 0: 540: 28.72
+	Hs
		646824 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KPCZ_HUMAN (58-699): 1.97e-174: 513: 28.92
+	Hs
		926956 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KPCZ_HUMAN (58-699): 1.97e-174: 513: 28.92
+	Hs
		397155 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KPCG_HUMAN (135-701): 9.7e-168: 499: 35.42
+	Hs
		683286 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KPCZ_HUMAN (58-699): 1.97e-174: 513: 28.92
+	Hs
		681770 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		AKT1_HUMAN (260-700): 1.81e-152: 452: 36.36
+	Hs
		681776 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		AKT1_HUMAN (260-700): 1.81e-152: 452: 36.36
+	Hs
		646741 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KS6A3_HUMAN (203-647): 7.6e-113: 358: 21.40
+	Hs
		683216 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KS6A3_HUMAN (203-647): 7.6e-113: 358: 21.40