HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: RON (Q04912)
Macrophage-stimulating protein receptor (MSP receptor) (EC 2.7.10.1) (CDw136) (Protein-tyrosine kinase 8) (p185-Ron) (CD antigen CD136) [Cleaved into: Macrophage-stimulating protein receptor alpha chain; Macrophage-stimulating protein receptor beta chain]
Gene: MST1R

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.55	1.00	0.743

Property	Details
Experiments	14505491, 12919677
Identification Methods	affinity chromatography technology, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1400
+	Hs
		909466 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		RON_HUMAN (19-1400): 0: 1277: 100.00
+	Hs
		926953 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		RON_HUMAN (19-1400): 0: 1277: 100.00
+	Mm
		554972 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MET_MOUSE (1-1362): 0: 1074: 33.78
+	Hs
		441479 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MET_HUMAN (1-1391): 0: 1065: 32.44
+	Hs
		601493 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		FGFR2_HUMAN (784-1397): 2.76e-113: 378: 23.33
+	Hs
		507877 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		FGFR1_HUMAN (767-1397): 8.56e-114: 379: 22.74
+	Hs
		609187 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		FGFR3_HUMAN (1015-1400): 5.83e-114: 379: 32.20
+	Hs
		601470 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		FGFR2_HUMAN (784-1397): 2.76e-113: 378: 23.33
+	Hs
		909494 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MERTK_HUMAN (1037-1348): 1.21e-59: 225: 37.65
+	Hs
		646846 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MERTK_HUMAN (1037-1348): 1.21e-59: 225: 37.65
+	Hs
		435597 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		674386 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47
+	Hs
		909560 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		FAK2_HUMAN (1075-1384): 4.28e-51: 199: 35.65
+	Hs
		674348 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		UFO_HUMAN (1062-1348): 3.97e-56: 213: 40.47
+	Hs
		435542 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		435604 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		435553 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		IGF1R_HUMAN (1072-1343): 3.56e-52: 204: 37.93
+	Hs
		782766 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CSK_HUMAN (1086-1344): 9.72e-51: 188: 40.00
+	Hs
		411315 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		INSR_HUMAN (1073-1338): 8.47e-51: 199: 38.73
+	Hs
		782768 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CSK_HUMAN (1086-1344): 9.72e-51: 188: 40.00