HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: DEMA (Q08495)
Dematin (Dematin actin-binding protein) (Erythrocyte membrane protein band 4.9)
Gene: DMTN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	33961781, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 405
+	Hs
		150550 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ABLM1_HUMAN (2-405): 7.68e-140: 419: 40.44
+	Hs
		150524 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ABLM1_HUMAN (2-405): 7.68e-140: 419: 40.44
+	Hs
		150553 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ABLM1_HUMAN (2-405): 7.68e-140: 419: 40.44
+	Hs
		150529 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		ABLM1_HUMAN (2-405): 7.68e-140: 419: 40.44
+	Hs
		909480 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DEMA_HUMAN (1-405): 5.45e-132: 386: 100.00
+	Hs
		926967 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		DEMA_HUMAN (1-405): 5.45e-132: 386: 100.00
+	Hs
		683294 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		DEMA_HUMAN (1-405): 5.45e-132: 386: 100.00
+	Mm
		926893 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		DEMA_MOUSE (1-405): 7.78e-126: 370: 96.05
+	Hs
		150530 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ABLM1_HUMAN (2-405): 7.68e-140: 419: 40.44
+	Hs
		150558 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		ABLM1_HUMAN (2-405): 7.68e-140: 419: 40.44
+	Hs
		683993 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		DEMA_HUMAN (1-405): 5.45e-132: 386: 100.00
+	At
		286685 14332_ARATH (3-243): 8.65e-144: 404: 61.22		VILI2_ARATH (128-405): 8.97e-47: 173: 16.34
+	Hs
		313793 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SVIL_HUMAN (148-405): 9.15e-45: 168: 17.69
+	Mm
		525125 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		GELS_MOUSE (42-299): 1.81e-47: 174: 10.04
+	Hs
		313756 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SVIL_HUMAN (148-405): 9.15e-45: 168: 17.69
+	Hs
		313800 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SVIL_HUMAN (148-405): 9.15e-45: 168: 17.69
+	Hs
		313759 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		SVIL_HUMAN (148-405): 9.15e-45: 168: 17.69
+	At
		286687 14333_ARATH (3-243): 8e-143: 401: 61.63		VILI3_ARATH (128-405): 7.09e-39: 150: 16.21
+	At
		286686 14331_ARATH (3-242): 2.67e-142: 400: 61.07		VILI3_ARATH (128-405): 7.09e-39: 150: 16.21
+	Hs
		313760 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		SVIL_HUMAN (148-405): 9.15e-45: 168: 17.69