HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: KIF5A (Q12840)
Kinesin heavy chain isoform 5A (Kinesin heavy chain neuron-specific 1) (Neuronal kinesin heavy chain) (NKHC)
Gene: KIF5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1032
+	Hs
		909493 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KIF5A_HUMAN (1-1032): 1e-154: 487: 100.00
+	Mm
		702835 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		KIF5A_MOUSE (1-1032): 6.83e-152: 479: 97.29
+	Hs
		910062 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KI13B_HUMAN (7-730): 3.75e-110: 378: 23.68
+	Hs
		231490 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KIF1B_HUMAN (6-757): 2.78e-109: 376: 23.61
+	Hs
		647306 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KI13B_HUMAN (7-730): 3.75e-110: 378: 23.68
+	Hs
		231455 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KIF1B_HUMAN (6-757): 2.78e-109: 376: 23.61
+	Hs
		231491 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KIF1B_HUMAN (6-757): 2.78e-109: 376: 23.61
+	Hs
		216917 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KIF1C_HUMAN (6-668): 1.81e-96: 332: 23.86
+	Hs
		216903 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KIF1C_HUMAN (6-668): 1.81e-96: 332: 23.86
+	Hs
		216920 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KIF1C_HUMAN (6-668): 1.81e-96: 332: 23.86
+	Hs
		702879 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45
+	Mm
		910258 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		KINH_MOUSE (623-1016): 3.55e-14: 79.5: 10.00
+	Mm
		659991 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KIF5C_MOUSE (477-1017): 2.72e-15: 83: 8.63
+	Hs
		229840 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20
+	Mm
		926803 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KINH_MOUSE (623-1016): 3.55e-14: 79.5: 10.00
+	Hs
		229850 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KIF5C_HUMAN (535-1017): 1.02e-14: 81: 9.20
+	Hs
		646668 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45
+	Hs
		702883 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KINH_HUMAN (623-1018): 3.31e-14: 79.5: 10.45
+	Mm
		910349 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		KI21B_MOUSE (238-756): 8.67e-09: 62.2: 10.83
+	Hs
		253246 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KI21B_HUMAN (250-858): 1.93e-10: 67.5: 10.51