Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: M3K12 (Q12852)
Mitogen-activated protein kinase kinase kinase 12 (EC 2.7.11.25) (Dual leucine zipper bearing kinase) (DLK) (Leucine-zipper protein kinase) (ZPK) (MAPK-upstream kinase) (MUK) (Mixed lineage kinase)
Gene: MAP3K12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 36736316
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains 14-3-3~PK_Tyr_Ser-Thr
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016020 - membrane
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 245
Hs

1 859
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Xl
+ Mm
+ Xl
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024