HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: STK4 (Q13043)
Serine/threonine-protein kinase 4 (EC 2.7.11.1) (Mammalian STE20-like protein kinase 1) (MST-1) (STE20-like kinase MST1) (Serine/threonine-protein kinase Krs-2) [Cleaved into: Serine/threonine-protein kinase 4 37kDa subunit (MST1/N); Serine/threonine-protein kinase 4 18kDa subunit (MST1/C)]
Gene: STK4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 487
+	Hs
		909502 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		STK4_HUMAN (1-487): 7.89e-170: 489: 100.00
+	Hs
		909512 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	Hs
		646859 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		STK3_HUMAN (1-487): 2.36e-147: 432: 72.47
+	At
		965291 14332_ARATH (3-243): 8.65e-144: 404: 61.22		CDPK1_ARATH (5-446): 2.41e-136: 408: 20.64
+	At
		802001 14334_ARATH (3-243): 2.7e-141: 398: 61.63		CDPK1_ARATH (5-446): 2.41e-136: 408: 20.64
+	At
		965360 14332_ARATH (3-243): 8.65e-144: 404: 61.22		CIPKC_ARATH (1-463): 1.46e-132: 394: 18.68
+	At
		788672 14333_ARATH (3-243): 8e-143: 401: 61.63		CIPKC_ARATH (1-463): 1.46e-132: 394: 18.68
+	At
		1280891 14337_ARATH (2-243): 2.78e-142: 400: 60.32		CIPKC_ARATH (1-463): 1.46e-132: 394: 18.68
+	Mm
		910231 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MARK3_MOUSE (29-425): 5.7e-124: 380: 22.44
+	Xl
		223344 O57468_XENLA (2-243): 4.53e-144: 404: 64.75		Q804T2_XENLA (29-451): 8.66e-125: 381: 21.74
+	Hs
		647862 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MARK3_HUMAN (29-451): 4.09e-123: 378: 21.32
+	Hs
		909730 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MARK2_HUMAN (6-486): 9.18e-123: 378: 20.68
+	Mm
		926780 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MARK3_MOUSE (29-425): 5.7e-124: 380: 22.44
+	Hs
		646650 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MARK3_HUMAN (29-451): 4.09e-123: 378: 21.32
+	Hs
		647041 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MARK2_HUMAN (6-486): 9.18e-123: 378: 20.68
+	Hs
		568616 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KAPCA_HUMAN (14-319): 7.68e-123: 364: 26.90
+	Hs
		610682 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KAPCB_HUMAN (14-319): 8.38e-123: 364: 25.63
+	Hs
		909810 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MINK1_HUMAN (10-336): 5.97e-73: 252: 42.32
+	Hs
		909881 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		M4K1_HUMAN (17-281): 2.36e-74: 252: 45.22
+	Hs
		647104 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MINK1_HUMAN (10-336): 5.97e-73: 252: 42.32