HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: M3K1 (Q13233)
Mitogen-activated protein kinase kinase kinase 1 (EC 2.7.11.25) (MAPK/ERK kinase kinase 1) (MEK kinase 1) (MEKK 1) (EC 2.3.2.27)
Gene: MAP3K1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21152872
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1512
+	Hs
		909513 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		M3K1_HUMAN (1-1512): 0: 1994: 100.00
+	Hs
		909585 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KPCD1_HUMAN (852-1510): 2.29e-124: 413: 16.89
+	Hs
		909621 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYLK3_HUMAN (792-1510): 2.74e-124: 410: 15.35
+	Zm
		45993 B6SRI4_MAIZE (1-243): 5.53e-143: 401: 59.92		A0A1Q0ZG94_MAIZE (840-1510): 2.6e-121: 413: 18.54
+	Hs
		397155 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KPCG_HUMAN (899-1509): 4.13e-124: 405: 16.04
+	At
		965360 14332_ARATH (3-243): 8.65e-144: 404: 61.22		CIPKC_ARATH (1220-1512): 1.06e-122: 394: 23.81
+	Hs
		166549 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DCLK1_HUMAN (996-1511): 1.41e-117: 389: 15.27
+	At
		788672 14333_ARATH (3-243): 8e-143: 401: 61.63		CIPKC_ARATH (1220-1512): 1.06e-122: 394: 23.81
+	At
		1280891 14337_ARATH (2-243): 2.78e-142: 400: 60.32		CIPKC_ARATH (1220-1512): 1.06e-122: 394: 23.81
+	At
		965291 14332_ARATH (3-243): 8.65e-144: 404: 61.22		CDPK1_ARATH (1094-1509): 4.85e-119: 389: 20.99
+	At
		802001 14334_ARATH (3-243): 2.7e-141: 398: 61.63		CDPK1_ARATH (1094-1509): 4.85e-119: 389: 20.99
+	Hs
		909811 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DCLK2_HUMAN (996-1508): 3.42e-114: 380: 16.03
+	Mm
		910345 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		DCLK1_MOUSE (996-1511): 2.86e-114: 380: 15.04
+	Hs
		909447 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK3_HUMAN (1243-1510): 4.87e-105: 338: 27.21
+	Hs
		625306 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CDK2_HUMAN (1243-1509): 1.1e-104: 337: 25.85
+	At
		788620 14333_ARATH (3-243): 8e-143: 401: 61.63		M3K2_ARATH (1243-1506): 5.21e-59: 218: 43.61
+	Hs
		909957 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		M3K3_HUMAN (1243-1505): 1.2e-51: 195: 44.03
+	Hs
		910191 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		M3K2_HUMAN (1238-1505): 3.52e-50: 191: 42.13
+	Hs
		909709 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		M3K15_HUMAN (1249-1509): 4.63e-42: 171: 36.84
+	Hs
		909955 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		M3K5_HUMAN (1249-1503): 1.95e-40: 166: 37.31