HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PDE3B (Q13370)
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B (EC 3.1.4.17) (CGIPDE1) (CGIP1) (Cyclic GMP-inhibited phosphodiesterase B) (CGI-PDE B)
Gene: PDE3B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.27	0.60	0.408

Property	Details
Experiments	22649097
Identification Methods	unspecified method
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 1112
+	Hs
		909520 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PDE3B_HUMAN (1-1112): 0: 1539: 100.00
+	Hs
		927008 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PDE3B_HUMAN (1-1112): 0: 1539: 100.00
+	Hs
		981979 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		PDE3B_HUMAN (1-1112): 0: 1539: 100.00
+	Hs
		904523 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		PDE3B_HUMAN (1-1112): 0: 1539: 100.00
+	Hs
		646886 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PDE3A_HUMAN (122-1105): 0: 1058: 44.22
+	Hs
		927039 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PDE3A_HUMAN (122-1105): 0: 1058: 44.22
+	Mm
		926778 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PDE4D_MOUSE (372-1100): 0: 552: 22.30
+	Mm
		926779 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PDE1B_MOUSE (592-1110): 1.28e-142: 441: 24.57
+	Mm
		926801 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PDE1A_MOUSE (592-1103): 1.52e-136: 426: 25.47
+	Hs
		872399 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PDE1A_HUMAN (592-1086): 7.59e-135: 421: 25.53
+	Hs
		909546 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PDE7A_HUMAN (662-1045): 7.35e-115: 366: 26.87
+	Hs
		910054 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PDE7B_HUMAN (656-1043): 3.14e-114: 363: 25.49
+	Hs
		927028 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PDE7A_HUMAN (662-1045): 7.35e-115: 366: 26.87
+	Hs
		647301 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PDE7B_HUMAN (656-1043): 3.14e-114: 363: 25.49
+	Hs
		927558 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PDE7B_HUMAN (656-1043): 3.14e-114: 363: 25.49
+	Hs
		683334 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PDE7A_HUMAN (662-1045): 7.35e-115: 366: 26.87
+	Hs
		683736 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PDE7B_HUMAN (656-1043): 3.14e-114: 363: 25.49
+	Hs
		905142 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		PDE7B_HUMAN (656-1043): 3.14e-114: 363: 25.49