HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.629

Property	Details
Experiments	36931259, 15161933
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1128
+	Hs
		909538 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ASPP2_HUMAN (1-1128): 0: 599: 100.00
+	Hs
		927020 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ASPP2_HUMAN (1-1128): 0: 599: 100.00
+	Hs
		909667 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		927153 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		927453 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83
+	Hs
		910023 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		883468 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		647273 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		646759 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		927522 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		883471 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		909789 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		646746 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DAPK1_HUMAN (791-1011): 1.31e-20: 100: 13.12
+	Hs
		161349 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		910111 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DAPLE_HUMAN (33-349): 6.45e-16: 85.6: 16.36
+	Hs
		161309 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		161353 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		647340 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DAPLE_HUMAN (33-349): 6.45e-16: 85.6: 16.36
+	Hs
		647248 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PP12C_HUMAN (906-1034): 4.04e-12: 72.6: 23.88
+	Hs
		927494 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PP12C_HUMAN (906-1034): 4.04e-12: 72.6: 23.88