HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019904 - protein domain specific binding GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 2115
+	Hs
		927055 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		NUMA1_HUMAN (1-2115): 1.36e-162: 555: 100.00
+	Hs
		909975 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08
+	Hs
		647234 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08
+	Zm
		5465 B6U284_MAIZE (1-243): 2.35e-143: 403: 59.92		A0A1D6DZK4_MAIZE (1170-2069): 4.65e-39: 162: 10.31
+	Mm
		926855 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MYH9_MOUSE (1089-2070): 6.61e-40: 165: 12.96
+	Hs
		522590 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH7_HUMAN (947-2023): 1.11e-36: 155: 11.21
+	Hs
		522602 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH7_HUMAN (947-2023): 1.11e-36: 155: 11.21
+	Mm
		926889 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PLEC_MOUSE (21-1207): 2.95e-35: 150: 12.47
+	Hs
		725130 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Hs
		646681 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		724761 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		647370 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH2_HUMAN (1-869): 2.82e-33: 143: 12.06
+	Hs
		646909 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PLEC_HUMAN (45-1230): 3.46e-32: 140: 13.37
+	Mm
		926804 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MYH10_MOUSE (5-834): 3.93e-31: 136: 11.65
+	Hs
		728460 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41
+	Hs
		502907 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH3_HUMAN (930-1731): 1.32e-24: 115: 12.39
+	Hs
		646685 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41
+	Hs
		728466 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41
+	Hs
		646893 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		GOGB1_HUMAN (1105-2077): 1.12e-19: 99.3: 9.49
+	Hs
		647371 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH13_HUMAN (6-516): 7.3e-15: 83.1: 10.66