HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: TAB1 (Q15750)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1)
Gene: TAB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0032991 - protein-containing complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 504
+	Hs
		909596 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		927077 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		683373 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		684057 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		982042 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		904599 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		273412 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PPM1B_HUMAN (30-381): 3.58e-83: 267: 13.65
+	Hs
		646686 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PPM1A_HUMAN (30-381): 4.24e-87: 274: 13.57
+	Hs
		728598 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PPM1A_HUMAN (30-381): 4.24e-87: 274: 13.57
+	Hs
		175369 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PPM1D_HUMAN (3-397): 1.41e-73: 245: 16.35
+	Ce
		107026 14332_CAEEL (3-241): 2.09e-116: 334: 77.41		TAB1_CAEEL (12-414): 1.51e-71: 234: 23.35