HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: SPEG (Q15772)
Striated muscle preferentially expressed protein kinase (EC 2.7.11.1) (Aortic preferentially expressed protein 1) (APEG-1)
Gene: SPEG

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.558

Property	Details
Experiments	33961781, 23444366
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 3267
+	Xl
		223344 O57468_XENLA (2-243): 4.53e-144: 404: 64.75		Q804T2_XENLA (2912-3247): 3.07e-114: 384: 22.94
+	Hs
		647862 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MARK3_HUMAN (2912-3224): 1.35e-112: 380: 23.98
+	Mm
		910231 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MARK3_MOUSE (2912-3224): 2.41e-112: 379: 24.29
+	Hs
		909531 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KCC2G_HUMAN (2954-3255): 1.51e-113: 376: 27.33
+	Hs
		646650 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MARK3_HUMAN (2912-3224): 1.35e-112: 380: 23.98
+	Mm
		926780 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MARK3_MOUSE (2912-3224): 2.41e-112: 379: 24.29
+	Hs
		647869 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MARK3_HUMAN (2912-3224): 1.35e-112: 380: 23.98
+	Hs
		910132 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DAPK2_HUMAN (2952-3248): 1.97e-42: 162: 32.80
+	Hs
		200101 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DAPK3_HUMAN (2955-3241): 7.55e-41: 160: 32.68
+	Hs
		646746 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DAPK1_HUMAN (2955-3219): 7.92e-39: 162: 34.30
+	Hs
		200087 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DAPK3_HUMAN (2955-3241): 7.55e-41: 160: 32.68
+	Hs
		910017 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYLK2_HUMAN (2770-3257): 2.58e-33: 140: 28.57
+	Hs
		909621 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYLK3_HUMAN (2784-3267): 3.49e-32: 139: 27.20
+	Hs
		647269 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYLK2_HUMAN (2770-3257): 2.58e-33: 140: 28.57
+	Hs
		255644 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		OBSL1_HUMAN (2230-2777): 2.74e-18: 95.1: 11.40
+	Hs
		255523 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		OBSL1_HUMAN (2230-2777): 2.74e-18: 95.1: 11.40
+	Hs
		255661 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		OBSL1_HUMAN (2230-2777): 2.74e-18: 95.1: 11.40
+	Hs
		647151 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TITIN_HUMAN (2393-2582): 1.38e-12: 76.6: 11.62
+	Hs
		82905 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		B9ZVR7_HUMAN (17-125): 1.17e-10: 69.6: 27.35
+	Hs
		82908 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		B9ZVR7_HUMAN (17-125): 1.17e-10: 69.6: 27.35