HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: AINX (Q16352)
Alpha-internexin (Alpha-Inx) (66 kDa neurofilament protein) (NF-66) (Neurofilament-66) (Neurofilament 5)
Gene: INA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0021762 - substantia nigra development
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 499
+	Hs
		909606 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		AINX_HUMAN (1-499): 1.25e-175: 504: 100.00
+	Mm
		804937 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		AINX_MOUSE (1-499): 1.06e-158: 461: 93.81
+	Mm
		804938 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		AINX_MOUSE (1-499): 1.06e-158: 461: 93.81
+	Hs
		684061 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		AINX_HUMAN (1-499): 1.25e-175: 504: 100.00
+	Hs
		982050 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		AINX_HUMAN (1-499): 1.25e-175: 504: 100.00
+	Mm
		440264 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		NFL_MOUSE (70-408): 3.17e-98: 308: 58.11
+	Hs
		443445 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91
+	Mm
		440289 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		NFM_MOUSE (9-476): 3.27e-94: 305: 46.88
+	Hs
		443346 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91
+	Hs
		443452 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91
+	Hs
		443356 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91
+	Hs
		569050 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DESM_HUMAN (57-418): 4.71e-85: 271: 51.38
+	Hs
		569067 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		DESM_HUMAN (57-418): 4.71e-85: 271: 51.38
+	Rn
		677657 1433B_RAT (1-242): 9.21e-126: 358: 81.41		VIME_RAT (73-418): 5.08e-97: 302: 55.20
+	Mm
		372933 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		GFAP_MOUSE (62-417): 4.51e-81: 260: 49.16
+	Hs
		443357 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91
+	Hs
		422160 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		NFL_HUMAN (70-408): 3.34e-97: 305: 58.11
+	Mm
		910243 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		K22O_MOUSE (56-417): 3.24e-58: 204: 31.15
+	Hs
		443469 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		VIME_HUMAN (73-418): 2.29e-96: 301: 54.91
+	Hs
		380460 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		K2C6B_HUMAN (59-410): 7.35e-59: 205: 30.23