HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: SMTL2 (Q2TAL5)
Smoothelin-like protein 2
Gene: SMTNL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	33961781, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 461
+	Hs
		909619 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SMTL2_HUMAN (1-461): 1.59e-160: 463: 100.00
+	Hs
		927101 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SMTL2_HUMAN (1-461): 1.59e-160: 463: 100.00
+	Hs
		683389 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		SMTL2_HUMAN (1-461): 1.59e-160: 463: 100.00
+	Mm
		926889 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		PLEC_MOUSE (166-460): 1.86e-66: 233: 20.51
+	Hs
		909641 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CYTSB_HUMAN (6-458): 2.82e-60: 214: 17.51
+	Hs
		646909 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PLEC_HUMAN (166-460): 3.06e-60: 215: 20.85
+	Hs
		646958 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CYTSB_HUMAN (6-458): 2.82e-60: 214: 17.51
+	Hs
		927068 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PLEC_HUMAN (166-460): 3.06e-60: 215: 20.85
+	Hs
		927123 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CYTSB_HUMAN (6-458): 2.82e-60: 214: 17.51
+	Hs
		646996 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CYTSA_HUMAN (165-457): 3.31e-58: 208: 24.03
+	Hs
		683406 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		CYTSB_HUMAN (6-458): 2.82e-60: 214: 17.51
+	Hs
		926965 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ACTN3_HUMAN (243-461): 9.42e-58: 206: 22.71
+	Hs
		211554 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ACTN4_HUMAN (339-458): 6.5e-54: 195: 34.17
+	Hs
		646682 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ACTN2_HUMAN (243-461): 9.94e-57: 203: 22.27
+	Hs
		725640 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ACTN2_HUMAN (243-461): 9.94e-57: 203: 22.27
+	Hs
		506805 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SPTB1_HUMAN (343-461): 4.65e-55: 200: 36.98
+	Mm
		926806 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		SPTB2_MOUSE (343-461): 8.3e-54: 196: 35.29
+	Hs
		926931 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SPTB2_HUMAN (343-461): 1.17e-53: 196: 35.29
+	Hs
		211558 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ACTN4_HUMAN (339-458): 6.5e-54: 195: 34.17
+	Hs
		684048 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		PLEC_HUMAN (166-460): 3.06e-60: 215: 20.85