HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: GRDN (Q3V6T2)
Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)
Gene: CCDC88A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 36931259
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007264 - small GTPase-mediated signal transduction GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1871
+	Hs
		909625 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		GRDN_HUMAN (1-1871): 2.19e-149: 509: 100.00
+	Mm
		910250 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		GRDN_MOUSE (1-1871): 5.17e-145: 497: 94.77
+	Mm
		926795 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		GRDN_MOUSE (1-1871): 5.17e-145: 497: 94.77
+	Zm
		5465 B6U284_MAIZE (1-243): 2.35e-143: 403: 59.92		A0A1D6DZK4_MAIZE (429-1871): 4.48e-57: 221: 11.97
+	Hs
		646681 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH9_HUMAN (1-809): 2.13e-29: 130: 10.02
+	Mm
		926855 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MYH9_MOUSE (1127-1871): 7.17e-29: 129: 8.24
+	Hs
		728460 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH11_HUMAN (3-722): 1.6e-26: 121: 12.80
+	Hs
		910111 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DAPLE_HUMAN (862-1846): 6.94e-26: 119: 11.33
+	Hs
		646685 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH11_HUMAN (3-722): 1.6e-26: 121: 12.80
+	Hs
		647340 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DAPLE_HUMAN (862-1846): 6.94e-26: 119: 11.33
+	Hs
		725130 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH10_HUMAN (43-620): 1.66e-20: 101: 9.86
+	Mm
		926804 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MYH10_MOUSE (4-625): 3.47e-22: 106: 10.69
+	Hs
		647371 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH13_HUMAN (49-679): 3.06e-21: 103: 10.35
+	Hs
		647069 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		HOOK3_HUMAN (14-554): 1.3e-16: 88.2: 23.48
+	Mm
		926886 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MY18A_MOUSE (477-1088): 4.6e-15: 83.6: 22.45
+	Hs
		909975 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CP250_HUMAN (1-682): 8.88e-13: 76.2: 11.44
+	Hs
		647234 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CP250_HUMAN (1-682): 8.88e-13: 76.2: 11.44
+	Mm
		93548 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		DESP_MOUSE (272-1150): 4.57e-10: 67.4: 19.30
+	Hs
		522590 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH7_HUMAN (1-391): 2.32e-10: 68.1: 12.25
+	Hs
		647370 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH2_HUMAN (1-392): 9.18e-09: 63.1: 10.69