HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: CE170 (Q5SW79)
Centrosomal protein of 170 kDa (Cep170) (KARP-1-binding protein) (KARP1-binding protein)
Gene: CEP170

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	36931259, 23444366, 15161933, 35709258
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1584
+	Hs
		909645 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Hs
		927128 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		CE170_HUMAN (1-1584): 0: 654: 100.00
+	Mm
		910273 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		CE170_MOUSE (1-1584): 0: 592: 88.00
+	Hs
		910199 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28
+	Hs
		647415 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		C170B_HUMAN (1-1560): 2.98e-111: 390: 28.28
+	Hs
		927045 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MDC1_HUMAN (29-1563): 8.72e-84: 307: 10.03
+	Hs
		909915 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		C170L_HUMAN (1275-1584): 2.13e-29: 121: 93.23
+	Hs
		647151 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TITIN_HUMAN (252-1467): 8.36e-24: 112: 8.68
+	Hs
		909712 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		OTOG_HUMAN (184-721): 3.18e-19: 97.1: 12.04
+	Hs
		910167 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SRRM2_HUMAN (122-1517): 1.29e-18: 95.3: 9.74
+	Hs
		647025 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		OTOG_HUMAN (184-721): 3.18e-19: 97.1: 12.04
+	Hs
		927196 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		OTOG_HUMAN (184-721): 3.18e-19: 97.1: 12.04
+	Hs
		909737 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		TICRR_HUMAN (438-1396): 4.55e-16: 86.8: 14.50
+	Hs
		909455 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65
+	Hs
		297821 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		K0754_HUMAN (564-1101): 7.33e-14: 79.4: 11.88
+	Hs
		647047 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TICRR_HUMAN (438-1396): 4.55e-16: 86.8: 14.50
+	Hs
		927220 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		TICRR_HUMAN (438-1396): 4.55e-16: 86.8: 14.50
+	Hs
		646808 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65
+	Hs
		926936 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ANK2_HUMAN (318-1298): 5e-14: 80.2: 13.65
+	Hs
		297824 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		K0754_HUMAN (564-1101): 7.33e-14: 79.4: 11.88