HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: RHG21 (Q5T5U3)
Rho GTPase-activating protein 21 (Rho GTPase-activating protein 10) (Rho-type GTPase-activating protein 21)
Gene: ARHGAP21

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1958
+	Hs
		909650 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		RHG21_HUMAN (1-1958): 0: 1739: 100.00
+	Hs
		70666 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYO9A_HUMAN (397-1626): 2.37e-163: 559: 13.41
+	Hs
		70649 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYO9A_HUMAN (397-1626): 2.37e-163: 559: 13.41
+	Hs
		909866 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ARAP2_HUMAN (461-1674): 2.78e-114: 404: 13.08
+	Mm
		910284 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		RHG33_MOUSE (813-1719): 4.74e-92: 330: 14.94
+	Hs
		909659 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SYDE2_HUMAN (609-1382): 2.99e-90: 323: 13.69
+	Hs
		49627 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		RHG10_HUMAN (883-1558): 8.64e-95: 328: 17.84
+	Hs
		909743 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SRGP1_HUMAN (1015-1671): 1.5e-88: 316: 18.66
+	Hs
		646982 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SYDE2_HUMAN (609-1382): 2.99e-90: 323: 13.69
+	Hs
		64684 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		RHG32_HUMAN (975-1909): 3.2e-84: 310: 16.63
+	Mm
		910285 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		SRGP3_MOUSE (1010-1639): 2.01e-86: 310: 17.76
+	Mm
		910322 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		SRGP2_MOUSE (652-1769): 1.01e-85: 307: 13.69
+	Hs
		253335 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SRGP2_HUMAN (652-1769): 9.4e-84: 302: 13.96
+	Hs
		64657 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		RHG32_HUMAN (975-1909): 3.2e-84: 310: 16.63
+	Hs
		253315 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SRGP2_HUMAN (652-1769): 9.4e-84: 302: 13.96
+	Hs
		909637 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		Q5JSD8_HUMAN (1160-1285): 4.53e-68: 226: 89.68
+	Hs
		646952 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		Q5JSD8_HUMAN (1160-1285): 4.53e-68: 226: 89.68
+	Hs
		506563 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		BCR_HUMAN (1142-1311): 4.29e-23: 110: 40.00
+	Mm
		926818 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		BCR_MOUSE (1142-1311): 4.04e-23: 110: 40.00
+	Hs
		506518 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		BCR_HUMAN (1142-1311): 4.29e-23: 110: 40.00