HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: WWC2 (Q6AWC2)
Protein WWC2 (BH-3-only member B) (WW domain-containing protein 2)
Gene: WWC2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	36931259, 15161933
Identification Methods	proximity labelling technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1192
+	Hs
		909674 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		WWC2_HUMAN (1-1192): 0: 1008: 100.00
+	Hs
		909790 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KIBRA_HUMAN (1-1192): 0: 810: 49.04
+	Hs
		647091 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		KIBRA_HUMAN (1-1192): 0: 810: 49.04
+	Hs
		647267 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		WWP1_HUMAN (6-136): 2.07e-35: 148: 23.78
+	Hs
		647191 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ITCH_HUMAN (7-143): 1.17e-33: 142: 24.66
+	Hs
		125318 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		WWP2_HUMAN (3-143): 4.17e-30: 131: 23.84
+	Hs
		125169 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		WWP2_HUMAN (3-143): 4.17e-30: 131: 23.84
+	Hs
		910022 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		SAV1_HUMAN (4-88): 3.52e-27: 117: 38.82
+	Mm
		808343 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NEDD4_MOUSE (54-164): 5.95e-20: 98.5: 19.30
+	Mm
		910341 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		RIMS2_MOUSE (556-832): 3.94e-13: 76.6: 13.78
+	Hs
		647296 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SMUF1_HUMAN (40-194): 1.56e-14: 80.8: 16.49
+	Hs
		808077 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NEDD4_HUMAN (1-173): 9.35e-12: 71.9: 15.64
+	Rn
		910358 1433E_RAT (2-243): 1.31e-144: 406: 63.53		NEDD4_RAT (1-241): 4.08e-10: 66.5: 15.32
+	Hs
		808460 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		YAP1_HUMAN (41-163): 9.64e-10: 64.5: 18.25
+	Hs
		646713 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NEDD4_HUMAN (1-173): 9.35e-12: 71.9: 15.64
+	Hs
		909930 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NED4L_HUMAN (1-141): 6.93e-09: 62.3: 18.37
+	Mm
		910302 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NED4L_MOUSE (1-141): 7.95e-09: 62.3: 17.01
+	Mm
		93264 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		E9PXB7_MOUSE (1-141): 7.04e-09: 62.3: 17.01
+	Hs
		646714 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		YAP1_HUMAN (41-163): 9.64e-10: 64.5: 18.25
+	Hs
		647201 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NED4L_HUMAN (1-141): 6.93e-09: 62.3: 18.37