HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: TET2 (Q6N021)
Methylcytosine dioxygenase TET2 (EC 1.14.11.80)
Gene: TET2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.50	0.578

Property	Details
Experiments	29735542, 36931259, 23353889
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 2002
+	Hs
		909681 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		927169 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		683446 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		684120 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		982143 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		904716 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		TET2_HUMAN (1-2002): 0: 3136: 100.00
+	Hs
		909832 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		647124 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		982300 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06
+	Hs
		904887 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		TET1_HUMAN (1844-2002): 1.37e-56: 220: 49.06