HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: RPTOR (Q8N122)
Regulatory-associated protein of mTOR (Raptor) (p150 target of rapamycin (TOR)-scaffold protein)
Gene: RPTOR

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18439900
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0071889 - 14-3-3 protein binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1335
+	Hs
		909801 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		RPTOR_HUMAN (1-1335): 0: 1440: 100.00
+	Mm
		933136 1433T_MOUSE (1-245): 2.96e-141: 397: 99.59		RPTOR_MOUSE (1-1335): 0: 1443: 96.55
+	Hs
		927290 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		RPTOR_HUMAN (1-1335): 0: 1440: 100.00
+	Hs
		909885 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18
+	Hs
		647171 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18
+	Hs
		927381 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18
+	Hs
		683605 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18
+	Hs
		903106 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		WDR5_HUMAN (1099-1334): 2.05e-64: 224: 16.88
+	Hs
		792954 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		LIS1_HUMAN (1101-1334): 4.69e-55: 199: 15.69
+	Hs
		792963 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		LIS1_HUMAN (1101-1334): 4.69e-55: 199: 15.69
+	Hs
		683188 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		LIS1_HUMAN (1101-1334): 4.69e-55: 199: 15.69
+	Hs
		684254 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		FBXW7_HUMAN (961-1324): 5.17e-69: 248: 15.18
+	Hs
		909952 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PI3R4_HUMAN (1102-1335): 7.12e-19: 95.3: 13.78
+	At
		965309 14332_ARATH (3-243): 8.65e-144: 404: 61.22		KTN84_ARATH (1076-1324): 1.66e-17: 90.6: 18.90
+	Hs
		683659 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PI3R4_HUMAN (1102-1335): 7.12e-19: 95.3: 13.78
+	At
		788540 14333_ARATH (3-243): 8e-143: 401: 61.63		PRL1_ARATH (1086-1324): 1.89e-14: 79.8: 19.58
+	Hs
		927391 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SNR40_HUMAN (1246-1335): 6.58e-16: 82.9: 17.58
+	Hs
		863399 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		COPA_HUMAN (1009-1182): 1.34e-10: 68.3: 17.62
+	Mm
		935526 1433F_MOUSE (2-242): 4.62e-106: 308: 71.43		SNR40_MOUSE (1246-1335): 9.32e-16: 82.5: 17.58
+	Mm
		222997 1433F_MOUSE (2-242): 4.62e-106: 308: 71.43		COPB2_MOUSE (1197-1333): 5.9e-15: 82.2: 15.83