HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: DCLK2 (Q8N568)
Serine/threonine-protein kinase DCLK2 (EC 2.7.11.1) (CaMK-like CREB regulatory kinase 2) (CL2) (CLICK-II) (CLICK2) (Doublecortin domain-containing protein 3B) (Doublecortin-like and CAM kinase-like 2) (Doublecortin-like kinase 2)
Gene: DCLK2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 766
+	Hs
		909811 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DCLK2_HUMAN (1-766): 0: 782: 100.00
+	Mm
		910275 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		DCLK2_MOUSE (1-766): 0: 767: 92.69
+	Hs
		166549 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DCLK1_HUMAN (1-744): 0: 675: 65.34
+	Mm
		910345 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		DCLK1_MOUSE (1-744): 0: 671: 62.57
+	Hs
		166534 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		DCLK1_HUMAN (1-744): 0: 675: 65.34
+	Hs
		910191 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		M3K2_HUMAN (9-651): 5.62e-145: 440: 18.69
+	Hs
		910114 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PAK5_HUMAN (9-658): 4.64e-139: 428: 21.48
+	Hs
		909957 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		M3K3_HUMAN (17-650): 4.69e-140: 427: 16.67
+	Hs
		647344 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PAK5_HUMAN (9-658): 4.64e-139: 428: 21.48
+	Hs
		647221 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		M3K3_HUMAN (17-650): 4.69e-140: 427: 16.67
+	At
		965291 14332_ARATH (3-243): 8.65e-144: 404: 61.22		CDPK1_ARATH (288-719): 8.11e-138: 421: 28.44
+	Mm
		292332 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		DCX_MOUSE (6-351): 1.51e-138: 414: 67.22
+	At
		802001 14334_ARATH (3-243): 2.7e-141: 398: 61.63		CDPK1_ARATH (288-719): 8.11e-138: 421: 28.44
+	Hs
		909531 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KCC2G_HUMAN (388-753): 7.49e-133: 407: 34.87
+	Hs
		909532 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KCC2D_HUMAN (388-698): 3.75e-133: 405: 37.46
+	Hs
		910174 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KCC2A_HUMAN (388-712): 8.55e-133: 403: 37.08
+	Mm
		926819 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KCC2D_MOUSE (388-698): 3.75e-133: 405: 37.46
+	Mm
		515221 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KCC2A_MOUSE (388-699): 1.12e-132: 403: 37.98
+	Mm
		659446 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KCC2B_MOUSE (388-760): 1.59e-131: 403: 33.25
+	Mm
		926866 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KCC2G_MOUSE (388-759): 1.42e-131: 402: 33.68