HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: KKCC1 (Q8N5S9)
Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)
Gene: CAMKK1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	32707033, 23444366
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 505
+	Hs
		909813 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Hs
		683541 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Rn
		910354 1433E_RAT (2-243): 1.31e-144: 406: 63.53		KKCC1_RAT (1-505): 3.01e-153: 448: 93.66
+	Rn
		716562 1433B_RAT (1-242): 9.21e-126: 358: 81.41		KKCC1_RAT (1-505): 3.01e-153: 448: 93.66
+	At
		965360 14332_ARATH (3-243): 8.65e-144: 404: 61.22		CIPKC_ARATH (103-501): 1.35e-132: 395: 23.47
+	At
		788672 14333_ARATH (3-243): 8e-143: 401: 61.63		CIPKC_ARATH (103-501): 1.35e-132: 395: 23.47
+	Dm
		90534 1433E_DROME (2-242): 6.77e-143: 401: 65.02		E1JGN0_DROME (20-415): 1.71e-125: 395: 28.29
+	At
		1280891 14337_ARATH (2-243): 2.78e-142: 400: 60.32		CIPKC_ARATH (103-501): 1.35e-132: 395: 23.47
+	Hs
		681770 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		AKT1_HUMAN (60-474): 9.07e-130: 387: 21.33
+	Hs
		681776 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		AKT1_HUMAN (60-474): 9.07e-130: 387: 21.33
+	Hs
		684209 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Hs
		982274 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Hs
		904856 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		KKCC1_HUMAN (1-505): 2.94e-159: 463: 100.00
+	Rn
		935723 1433F_RAT (2-242): 4.62e-106: 308: 71.43		KKCC1_RAT (1-505): 3.01e-153: 448: 93.66
+	Rn
		905365 1433G_RAT (1-242): 5.48e-105: 305: 70.33		KKCC1_RAT (1-505): 3.01e-153: 448: 93.66
+	Hs
		684282 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		KKCC2_HUMAN (31-504): 7.59e-134: 401: 59.49
+	Hs
		681682 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		AKT1_HUMAN (60-474): 9.07e-130: 387: 21.33
+	Hs
		681766 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		AKT1_HUMAN (60-474): 9.07e-130: 387: 21.33