HitPredict

Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2087 Hs			1 839
+	Hs
		64712 RHG32_HUMAN (1-2087): 0: 1424: 100.00		NTRK2_HUMAN (6-839): 0: 557: 52.87
+	Mm
		546314 RHG32_MOUSE (1-2087): 0: 1404: 87.28		NTRK2_MOUSE (6-839): 0: 555: 53.29
+	Hs
		64640 RHG32_HUMAN (1-2087): 0: 1424: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		64694 RHG32_HUMAN (1-2087): 0: 1424: 100.00		ROR1_HUMAN (509-821): 2.63e-67: 243: 40.50
+	Hs
		64695 RHG32_HUMAN (1-2087): 0: 1424: 100.00		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		64625 RHG32_HUMAN (1-2087): 0: 1424: 100.00		MUSK_HUMAN (209-391): 1.75e-22: 105: 24.60
+	Hs
		993022 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		384788 MYO9B_HUMAN (43-823): 2.74e-75: 281: 13.14		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		253302 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		384998 RHG17_HUMAN (189-1018): 1.7e-69: 255: 14.81		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		385580 RHG35_HUMAN (9-584): 3.79e-67: 254: 16.47		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		253307 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		508041 RHG29_HUMAN (134-911): 5.44e-66: 249: 11.78		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		507972 ABR_HUMAN (350-569): 2.79e-66: 245: 32.89		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		507962 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		607950 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Rn
		88969 D4A9G6_RAT (67-1276): 6.25e-110: 386: 31.39		INSR_RAT (513-824): 3.31e-62: 230: 38.80
+	Hs
		253341 SRGP2_HUMAN (191-939): 6.03e-73: 268: 16.21		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		411366 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		435622 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16