HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PK3C3 (Q8NEB9)
Phosphatidylinositol 3-kinase catalytic subunit type 3 (PI3-kinase type 3) (PI3K type 3) (PtdIns-3-kinase type 3) (EC 2.7.1.137) (Phosphatidylinositol 3-kinase p100 subunit) (Phosphoinositide-3-kinase class 3) (hVps34)
Gene: PIK3C3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	7479742
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 887
+	Hs
		927318 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PK3C3_HUMAN (1-887): 0: 999: 100.00
+	Hs
		646704 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PK3CB_HUMAN (43-886): 0: 586: 21.06
+	Hs
		128836 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		P3C2A_HUMAN (112-883): 6.36e-147: 476: 20.64
+	Hs
		128810 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		P3C2A_HUMAN (112-883): 6.36e-147: 476: 20.64
+	Hs
		128838 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		P3C2A_HUMAN (112-883): 6.36e-147: 476: 20.64
+	Hs
		128813 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		P3C2A_HUMAN (112-883): 6.36e-147: 476: 20.64
+	At
		788647 14333_ARATH (3-243): 8e-143: 401: 61.63		ATM_ARATH (175-884): 9.74e-126: 421: 15.47
+	Dm
		664613 1433Z_DROME (1-245): 3.68e-141: 397: 77.14		Q7K3H0_DROME (195-883): 3.52e-127: 423: 19.50
+	Hs
		128814 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		P3C2A_HUMAN (112-883): 6.36e-147: 476: 20.64
+	Hs
		128844 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		P3C2A_HUMAN (112-883): 6.36e-147: 476: 20.64
+	Hs
		910120 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PI4KB_HUMAN (605-884): 2.87e-86: 295: 25.34
+	Hs
		647352 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PI4KB_HUMAN (605-884): 2.87e-86: 295: 25.34
+	Hs
		927618 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PI4KB_HUMAN (605-884): 2.87e-86: 295: 25.34
+	Hs
		683785 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		PI4KB_HUMAN (605-884): 2.87e-86: 295: 25.34
+	Hs
		684374 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		PI4KB_HUMAN (605-884): 2.87e-86: 295: 25.34
+	Hs
		135774 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		P3C2B_HUMAN (31-478): 1.7e-26: 119: 14.66
+	Hs
		135766 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		P3C2B_HUMAN (31-478): 1.7e-26: 119: 14.66
+	Hs
		135776 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		P3C2B_HUMAN (31-478): 1.7e-26: 119: 14.66
+	Hs
		135769 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		P3C2B_HUMAN (31-478): 1.7e-26: 119: 14.66
+	Hs
		135770 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		P3C2B_HUMAN (31-478): 1.7e-26: 119: 14.66