HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1356
+	Hs
		909852 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		909853 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Hs
		647136 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Dm
		955046 1433E_DROME (2-242): 6.77e-143: 401: 65.02		Q9VX75_DROME (1-1082): 3.49e-78: 286: 21.87
+	Dm
		664665 1433Z_DROME (1-245): 3.68e-141: 397: 77.14		Q9VX75_DROME (1-1082): 3.49e-78: 286: 21.87
+	Dm
		954995 1433E_DROME (2-242): 6.77e-143: 401: 65.02		Q0KHR3_DROME (42-1082): 6.25e-62: 235: 20.76
+	Rn
		910361 1433E_RAT (2-243): 1.31e-144: 406: 63.53		RIMS1_RAT (314-947): 2.11e-50: 198: 17.14
+	Rn
		926903 1433Z_RAT (1-245): 3.06e-142: 399: 80.00		RIMS1_RAT (314-947): 2.11e-50: 198: 17.14
+	Mm
		910260 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Mm
		926805 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Mm
		926859 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		LNX2_MOUSE (15-361): 1.42e-19: 97: 11.11
+	Hs
		909498 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		646848 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		926984 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Mm
		250606 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		LNX1_MOUSE (130-385): 1.31e-14: 80.8: 15.33
+	Mm
		250609 1433T_MOUSE (1-245): 2.96e-141: 397: 99.59		LNX1_MOUSE (130-385): 1.31e-14: 80.8: 15.33
+	Hs
		646827 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		926961 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		646881 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		927034 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75