HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: AKTS1 (Q96B36)
Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate)
Gene: AKT1S1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	33961781, 23444366, 15161933, 28514442
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 256
+	Hs
		909890 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00
+	Hs
		927386 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00
+	Hs
		683608 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00
+	Mm
		933141 1433T_MOUSE (1-245): 2.96e-141: 397: 99.59		AKTS1_MOUSE (1-256): 1.59e-121: 348: 92.61
+	Hs
		982365 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00
+	Hs
		904962 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		AKTS1_HUMAN (1-256): 4.07e-135: 382: 100.00