HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: EDC3 (Q96F86)
Enhancer of mRNA-decapping protein 3 (LSM16 homolog) (YjeF N-terminal domain-containing protein 2) (YjeF_N2) (hYjeF_N2) (YjeF domain-containing protein 1)
Gene: EDC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.687

Property	Details
Experiments	17353931, 33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 508
+	Hs
		909901 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		927395 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		683616 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Mm
		910312 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		EDC3_MOUSE (1-508): 0: 826: 95.67
+	Hs
		684260 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		982373 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		EDC3_HUMAN (1-508): 0: 846: 100.00
+	Hs
		904972 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		EDC3_HUMAN (1-508): 0: 846: 100.00