HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: FRMD6 (Q96NE9)
FERM domain-containing protein 6 (Willin)
Gene: FRMD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	24366813, 33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 622
+	Hs
		909922 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		FRMD6_HUMAN (1-622): 1.67e-171: 503: 100.00
+	Hs
		909498 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		646848 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN13_HUMAN (14-401): 8.49e-120: 394: 24.49
+	Hs
		647300 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L5_HUMAN (5-598): 2.32e-127: 393: 14.73
+	Hs
		663970 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN4_HUMAN (4-536): 8.69e-120: 379: 14.29
+	Hs
		646653 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN4_HUMAN (4-536): 8.69e-120: 379: 14.29
+	Hs
		910025 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		E41L1_HUMAN (18-573): 2.35e-114: 364: 15.00
+	Hs
		910185 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		E41L3_HUMAN (13-569): 1.1e-111: 361: 13.81
+	Hs
		647274 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L1_HUMAN (18-573): 2.35e-114: 364: 15.00
+	Hs
		505612 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		EPB41_HUMAN (14-572): 1.19e-110: 353: 14.83
+	Hs
		505557 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		EPB41_HUMAN (14-572): 1.19e-110: 353: 14.83
+	Hs
		204644 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		204614 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		E41L2_HUMAN (13-545): 1.19e-105: 343: 12.70
+	Hs
		640229 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Hs
		647056 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		FRMD5_HUMAN (1-528): 6e-107: 335: 19.04
+	Hs
		640212 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN3_HUMAN (5-547): 9.8e-102: 331: 14.19
+	Mm
		910287 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		FRM4A_MOUSE (12-334): 6.2e-85: 288: 19.64
+	Mm
		910323 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		FRM4B_MOUSE (12-379): 1.15e-74: 260: 19.06
+	Hs
		909595 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75
+	Hs
		646918 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PTN14_HUMAN (20-336): 1.44e-73: 258: 19.75