HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: CEP89 (Q96ST8)
Centrosomal protein of 89 kDa (Cep89) (Centrosomal protein 123) (Cep123) (Coiled-coil domain-containing protein 123)
Gene: CEP89

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.70	0.60	0.650

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 783
+	Hs
		909942 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CEP89_HUMAN (1-783): 8.03e-53: 198: 100.00
+	Hs
		909658 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		646981 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MRCKA_HUMAN (197-717): 8.92e-48: 186: 17.03
+	Hs
		646681 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH9_HUMAN (268-774): 1.96e-23: 109: 12.33
+	Hs
		647370 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH2_HUMAN (63-644): 1.82e-23: 109: 9.56
+	Hs
		724761 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH9_HUMAN (268-774): 1.96e-23: 109: 12.33
+	Mm
		926855 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MYH9_MOUSE (268-774): 1.76e-22: 105: 12.13
+	Hs
		522590 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH7_HUMAN (253-782): 3.21e-20: 98.6: 11.28
+	Hs
		522602 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH7_HUMAN (253-782): 3.21e-20: 98.6: 11.28
+	Mm
		926886 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MY18A_MOUSE (49-523): 4.23e-19: 95.2: 10.63
+	Hs
		728460 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH11_HUMAN (27-481): 5.52e-14: 78.6: 8.90
+	Hs
		646685 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH11_HUMAN (27-481): 5.52e-14: 78.6: 8.90
+	Hs
		647371 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH13_HUMAN (40-521): 4.68e-14: 78.6: 8.71
+	Hs
		728466 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH11_HUMAN (27-481): 5.52e-14: 78.6: 8.90
+	Hs
		725130 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MYH10_HUMAN (451-777): 3.75e-11: 69.4: 10.61
+	Hs
		502907 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH3_HUMAN (38-512): 4.58e-12: 72.1: 10.46
+	Hs
		909488 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CGNL1_HUMAN (7-322): 5.73e-09: 62: 10.53
+	Mm
		926804 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MYH10_MOUSE (451-777): 6.14e-11: 68.6: 10.30
+	Hs
		551660 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		DESP_HUMAN (240-774): 6.79e-11: 68.5: 14.29
+	Hs
		646838 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		CGNL1_HUMAN (7-322): 5.73e-09: 62: 10.53