HitPredict

Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: DZIP3 (Q86Y13)
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138)
Gene: DZIP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.523

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 2087 Hs			1 1208
+	Hs
		64718 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RNF43_HUMAN (1104-1206): 7.85e-24: 110: 26.79
+	Hs
		64621 RHG32_HUMAN (1-2087): 0: 1424: 100.00		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		1051315 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		DCTN1_HUMAN (639-961): 5.05e-41: 167: 15.84
+	Hs
		148770 MYO9B_HUMAN (43-823): 2.74e-75: 281: 13.14		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		1133673 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		RNF43_HUMAN (1104-1206): 7.85e-24: 110: 26.79
+	Hs
		993034 RHG01_HUMAN (188-572): 1.29e-69: 243: 18.09		SYVN1_HUMAN (1108-1192): 8.82e-15: 80.9: 32.58