HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: WWP1 (Q9H0M0)
NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
Gene: WWP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	15161933
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0045892 - negative regulation of DNA-templated transcription GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 922
+	Hs
		647191 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ITCH_HUMAN (1-922): 0: 884: 57.14
+	Hs
		125318 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125169 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125351 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		909930 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NED4L_HUMAN (1-919): 0: 822: 33.16
+	Mm
		910302 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NED4L_MOUSE (8-919): 0: 817: 33.23
+	Hs
		647201 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NED4L_HUMAN (1-919): 0: 822: 33.16
+	Hs
		927423 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		NED4L_HUMAN (1-919): 0: 822: 33.16
+	Hs
		808077 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Hs
		646713 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Hs
		808081 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Mm
		93264 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		E9PXB7_MOUSE (129-919): 0: 696: 34.71
+	Mm
		93266 1433T_MOUSE (1-245): 2.96e-141: 397: 99.59		E9PXB7_MOUSE (129-919): 0: 696: 34.71
+	Hs
		909745 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		HUWE1_HUMAN (130-921): 1.4e-172: 559: 24.48
+	Hs
		927228 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		HUWE1_HUMAN (130-921): 1.4e-172: 559: 24.48
+	At
		788566 14333_ARATH (3-243): 8e-143: 401: 61.63		UPL2_ARATH (430-920): 1.83e-159: 520: 33.14
+	Mm
		808343 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NEDD4_MOUSE (3-446): 4.73e-51: 195: 18.83
+	Rn
		910358 1433E_RAT (2-243): 1.31e-144: 406: 63.53		NEDD4_RAT (10-425): 7.95e-51: 195: 19.38
+	Rn
		933150 1433T_RAT (1-245): 2.96e-141: 397: 99.59		NEDD4_RAT (10-425): 7.95e-51: 195: 19.38
+	Hs
		647296 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SMUF1_HUMAN (6-451): 5.28e-38: 154: 15.82