HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: OSBL3 (Q9H4L5)
Oxysterol-binding protein-related protein 3 (ORP-3) (OSBP-related protein 3)
Gene: OSBPL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 887
+	Hs
		910026 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		OSBL3_HUMAN (1-887): 0: 943: 100.00
+	Hs
		927525 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		OSBL3_HUMAN (1-887): 0: 943: 100.00
+	Hs
		683711 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		OSBL3_HUMAN (1-887): 0: 943: 100.00
+	Hs
		909995 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		OSBL6_HUMAN (1-887): 0: 852: 55.94
+	Hs
		684325 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		OSBL3_HUMAN (1-887): 0: 943: 100.00
+	Hs
		647246 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		OSBL6_HUMAN (1-887): 0: 852: 55.94
+	Hs
		982497 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		OSBL3_HUMAN (1-887): 0: 943: 100.00
+	Hs
		927492 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		OSBL6_HUMAN (1-887): 0: 852: 55.94
+	Hs
		683686 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		OSBL6_HUMAN (1-887): 0: 852: 55.94
+	Hs
		982462 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		OSBL6_HUMAN (1-887): 0: 852: 55.94
+	Hs
		905080 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		OSBL6_HUMAN (1-887): 0: 852: 55.94
+	Hs
		905079 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		OSBL7_HUMAN (17-887): 0: 790: 48.52
+	Hs
		909994 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		OSBL8_HUMAN (159-883): 1.23e-157: 486: 17.56
+	Hs
		927491 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		OSBL8_HUMAN (159-883): 1.23e-157: 486: 17.56
+	Hs
		982461 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		OSBL8_HUMAN (159-883): 1.23e-157: 486: 17.56
+	Hs
		905078 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		OSBL8_HUMAN (159-883): 1.23e-157: 486: 17.56
+	Hs
		982482 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		OSBL5_HUMAN (329-883): 3.78e-146: 455: 16.87
+	Mm
		935568 1433F_MOUSE (2-242): 4.62e-106: 308: 71.43		OSB11_MOUSE (57-362): 1.65e-43: 171: 12.90
+	Hs
		982447 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		OSB10_HUMAN (37-385): 3.57e-34: 142: 14.92
+	Hs
		905067 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		OSB10_HUMAN (37-385): 3.57e-34: 142: 14.92