HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: REEP4 (Q9H6H4)
Receptor expression-enhancing protein 4
Gene: REEP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.50	0.630

Property	Details
Experiments	33961781, 35271311, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 257
+	Hs
		910029 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		REEP4_HUMAN (1-257): 1.84e-108: 315: 100.00
+	Hs
		927531 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		REEP4_HUMAN (1-257): 1.84e-108: 315: 100.00
+	Hs
		683713 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		REEP4_HUMAN (1-257): 1.84e-108: 315: 100.00
+	Hs
		909682 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		REEP3_HUMAN (1-249): 3.52e-88: 263: 53.10
+	Hs
		647003 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		REEP3_HUMAN (1-249): 3.52e-88: 263: 53.10
+	Hs
		927170 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		REEP3_HUMAN (1-249): 3.52e-88: 263: 53.10
+	Hs
		909967 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		REEP2_HUMAN (1-257): 5.2e-84: 253: 52.69
+	Hs
		683447 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		REEP3_HUMAN (1-249): 3.52e-88: 263: 53.10
+	Hs
		927467 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		REEP2_HUMAN (1-257): 5.2e-84: 253: 52.69
+	Hs
		683673 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		REEP2_HUMAN (1-257): 5.2e-84: 253: 52.69
+	Hs
		684326 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		REEP4_HUMAN (1-257): 1.84e-108: 315: 100.00
+	Hs
		910038 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		REEP1_HUMAN (1-160): 4.17e-71: 218: 73.13
+	Hs
		927540 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		REEP1_HUMAN (1-160): 4.17e-71: 218: 73.13
+	Hs
		927402 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		REEP6_HUMAN (1-181): 2.42e-61: 193: 25.28
+	Hs
		683272 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		REEP5_HUMAN (1-125): 1.01e-59: 188: 35.71
+	Hs
		684122 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		REEP3_HUMAN (1-249): 3.52e-88: 263: 53.10
+	At
		788367 14331_ARATH (3-242): 2.67e-142: 400: 61.07		HA22K_ARATH (1-167): 6.25e-53: 172: 23.70
+	Hs
		982144 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		REEP3_HUMAN (1-249): 3.52e-88: 263: 53.10
+	Hs
		982435 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		REEP2_HUMAN (1-257): 5.2e-84: 253: 52.69
+	Zm
		42212 B6SRI4_MAIZE (1-243): 5.53e-143: 401: 59.92		A0A1D6NY22_MAIZE (9-61): 4.02e-20: 83.1: 30.19