HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: PKHA2 (Q9HB19)
Pleckstrin homology domain-containing family A member 2 (PH domain-containing family A member 2) (Tandem PH domain-containing protein 2) (TAPP-2)
Gene: PLEKHA2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	19786618, 36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016020 - membrane GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 425
+	Hs
		910041 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHA2_HUMAN (1-425): 2.61e-152: 439: 100.00
+	Hs
		910043 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHA1_HUMAN (1-425): 7.64e-108: 325: 44.21
+	Hs
		309464 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MTMR5_HUMAN (3-298): 4.14e-49: 181: 17.56
+	Hs
		309444 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MTMR5_HUMAN (3-298): 4.14e-49: 181: 17.56
+	Mm
		926821 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MTMR5_MOUSE (3-298): 3.99e-48: 178: 16.93
+	Hs
		909830 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		DP13B_HUMAN (91-418): 1.55e-39: 152: 13.21
+	Hs
		909680 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHA7_HUMAN (118-420): 6.77e-39: 151: 16.81
+	Hs
		910040 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHA5_HUMAN (118-392): 3.97e-37: 146: 15.05
+	Hs
		909582 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ACAP2_HUMAN (15-361): 3.99e-37: 145: 16.00
+	At
		788659 14333_ARATH (3-243): 8e-143: 401: 61.63		DRP2A_ARATH (56-317): 2.28e-38: 149: 17.36
+	Hs
		647001 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PKHA7_HUMAN (118-420): 6.77e-39: 151: 16.81
+	At
		965340 14332_ARATH (3-243): 8.65e-144: 404: 61.22		DRP2B_ARATH (56-317): 2.92e-36: 143: 17.63
+	Hs
		909720 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		PKHM3_HUMAN (12-305): 4.88e-35: 139: 14.82
+	Mm
		910229 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		MPRIP_MOUSE (119-388): 8.39e-35: 139: 14.80
+	Hs
		909703 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MPRIP_HUMAN (110-388): 7.33e-34: 136: 15.09
+	Mm
		910223 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		CYH2_MOUSE (134-322): 2.53e-34: 133: 21.50
+	Hs
		647030 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		PKHM3_HUMAN (12-305): 4.88e-35: 139: 14.82
+	Hs
		647021 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MPRIP_HUMAN (110-388): 7.33e-34: 136: 15.09
+	Hs
		909866 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ARAP2_HUMAN (185-326): 3.94e-12: 70.4: 18.18
+	Hs
		647152 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ARAP2_HUMAN (185-326): 3.94e-12: 70.4: 18.18