HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: MLXPL (Q9NP71)
Carbohydrate-responsive element-binding protein (ChREBP) (Class D basic helix-loop-helix protein 14) (bHLHd14) (MLX interactor) (MLX-interacting protein-like) (WS basic-helix-loop-helix leucine zipper protein) (WS-bHLH) (Williams-Beuren syndrome chromosomal region 14 protein)
Gene: MLXIPL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 852
+	Hs
		927559 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MLXPL_HUMAN (13-852): 6.6e-115: 372: 100.00
+	Hs
		910039 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MLXIP_HUMAN (41-844): 6.68e-78: 273: 39.14
+	Hs
		647289 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MLXIP_HUMAN (41-844): 6.68e-78: 273: 39.14
+	Hs
		927544 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MLXIP_HUMAN (41-844): 6.68e-78: 273: 39.14
+	Hs
		683723 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		MLXIP_HUMAN (41-844): 6.68e-78: 273: 39.14
+	Hs
		297821 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		K0754_HUMAN (293-844): 6.68e-29: 127: 12.66
+	Hs
		910128 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MLX_HUMAN (558-822): 1.27e-29: 121: 26.77
+	Hs
		297824 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		K0754_HUMAN (293-844): 6.68e-29: 127: 12.66
+	Hs
		297815 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		K0754_HUMAN (293-844): 6.68e-29: 127: 12.66
+	Hs
		927628 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MLX_HUMAN (558-822): 1.27e-29: 121: 26.77
+	Hs
		909712 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		OTOG_HUMAN (374-844): 1.71e-18: 93.3: 10.06
+	Hs
		647025 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		OTOG_HUMAN (374-844): 1.71e-18: 93.3: 10.06
+	Hs
		927196 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		OTOG_HUMAN (374-844): 1.71e-18: 93.3: 10.06
+	Hs
		683472 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		OTOG_HUMAN (374-844): 1.71e-18: 93.3: 10.06
+	Hs
		257595 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ANR17_HUMAN (243-688): 5.19e-09: 62.4: 12.15
+	Hs
		647151 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		TITIN_HUMAN (374-544): 3.34e-10: 66.5: 20.20
+	Hs
		927352 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		TITIN_HUMAN (374-544): 3.34e-10: 66.5: 20.20
+	Hs
		257566 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ANR17_HUMAN (243-688): 5.19e-09: 62.4: 12.15
+	Hs
		257597 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ANR17_HUMAN (243-688): 5.19e-09: 62.4: 12.15
+	Hs
		257572 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		ANR17_HUMAN (243-688): 5.19e-09: 62.4: 12.15