HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: MTMR4 (Q9NYA4)
Myotubularin-related protein 4 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Zinc finger FYVE domain-containing protein 11)
Gene: MTMR4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	28675297, 33961781, 36931259, 28514442
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1195
+	Hs
		910087 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MTMR4_HUMAN (1-1195): 0: 1246: 100.00
+	Hs
		927584 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MTMR4_HUMAN (1-1195): 0: 1246: 100.00
+	Hs
		909535 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MTMR3_HUMAN (1-1195): 0: 1019: 47.63
+	Hs
		927016 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MTMR3_HUMAN (1-1195): 0: 1019: 47.63
+	Hs
		683328 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		MTMR3_HUMAN (1-1195): 0: 1019: 47.63
+	Mm
		926899 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MTMR1_MOUSE (14-630): 0: 727: 28.37
+	Hs
		909534 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MTMR2_HUMAN (7-630): 0: 716: 32.77
+	Hs
		309464 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MTMR5_HUMAN (161-802): 8.65e-151: 499: 21.79
+	Mm
		926821 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		MTMR5_MOUSE (161-802): 7.58e-152: 501: 22.07
+	Hs
		309444 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MTMR5_HUMAN (161-802): 8.65e-151: 499: 21.79
+	Hs
		927581 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MTMRA_HUMAN (6-625): 2.53e-157: 490: 19.89
+	Hs
		910000 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		647255 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		927499 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MTMRC_HUMAN (6-550): 9.99e-132: 422: 18.87
+	Hs
		909717 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		647028 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		927201 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		FGD6_HUMAN (610-1195): 4.14e-79: 288: 14.93
+	Hs
		909944 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00
+	Hs
		647212 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00
+	Hs
		927439 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		RUFY1_HUMAN (974-1173): 7.3e-41: 163: 27.00