HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: KDM5B (Q9UGL1)
Lysine-specific demethylase 5B (EC 1.14.11.67) (Cancer/testis antigen 31) (CT31) (Histone demethylase JARID1B) (Jumonji/ARID domain-containing protein 1B) (PLU-1) (Retinoblastoma-binding protein 2 homolog 1) (RBP2-H1) ([histone H3]-trimethyl-L-lysine(4) demethylase 5B)
Gene: KDM5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0045892 - negative regulation of DNA-templated transcription
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 1544
+	Hs
		910127 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KDM5B_HUMAN (1-1544): 0: 1153: 100.00
+	Hs
		927627 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KDM5B_HUMAN (1-1544): 0: 1153: 100.00
+	Hs
		683791 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KDM5B_HUMAN (1-1544): 0: 1153: 100.00
+	Hs
		982592 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		KDM5B_HUMAN (1-1544): 0: 1153: 100.00
+	Hs
		905221 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		KDM5B_HUMAN (1-1544): 0: 1153: 100.00
+	Hs
		666525 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		KDM5A_HUMAN (17-1332): 0: 951: 55.26
+	Hs
		909479 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		GOGA3_HUMAN (639-1478): 4.29e-88: 319: 13.54
+	Hs
		522590 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		MYH7_HUMAN (744-1483): 4.88e-86: 314: 13.12
+	Hs
		522602 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MYH7_HUMAN (744-1483): 4.88e-86: 314: 13.12
+	Mm
		879489 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		GOGA3_MOUSE (764-1486): 2.25e-15: 84.3: 12.29