HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: LIMA1 (Q9UHB6)
LIM domain and actin-binding protein 1 (Epithelial protein lost in neoplasm)
Gene: LIMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.60	0.619

Property	Details
Experiments	36931259, 15161933
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 759
+	Hs
		910129 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		927629 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		683794 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		684379 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		982595 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		905224 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		LIMA1_HUMAN (1-759): 0: 855: 100.00
+	Hs
		909807 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		927298 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		683538 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		150550 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		150524 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		150553 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		150529 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		982269 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		904849 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		MILK1_HUMAN (355-540): 3.05e-31: 133: 21.81
+	Hs
		150530 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		150558 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		150547 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		ABLM1_HUMAN (298-548): 8.97e-23: 106: 11.28
+	Hs
		684040 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		LASP1_HUMAN (390-480): 2.66e-11: 66.8: 25.00