HitPredict

Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	25416956, 29395067
Identification Methods	two hybrid, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2087 Hs			1 669
+	Mm
		1195014 RHG32_MOUSE (1-2087): 0: 1404: 87.28		TSC1_MOUSE (48-630): 3.36e-32: 135: 13.67
+	Hs
		64716 RHG32_HUMAN (1-2087): 0: 1424: 100.00		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		64621 RHG32_HUMAN (1-2087): 0: 1424: 100.00		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		147860 RHG33_HUMAN (74-1276): 2.2e-113: 395: 30.98		SMCA2_HUMAN (18-531): 1.58e-34: 143: 13.60
+	Hs
		70704 MYO9A_HUMAN (346-832): 3.49e-66: 252: 20.35		LZTS2_HUMAN (1-669): 6.28e-56: 203: 100.00
+	Hs
		200209 SRGP3_HUMAN (294-939): 5.72e-78: 284: 17.36		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Mm
		64329 RHG31_MOUSE (350-1662): 1.79e-86: 315: 23.18		ITSN1_MOUSE (3-554): 8.1e-12: 70.8: 12.08
+	Hs
		1133710 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		MYO5C_HUMAN (318-668): 7.57e-17: 87.4: 12.02
+	Hs
		1078833 RHG31_HUMAN (358-1637): 5.78e-63: 240: 21.26		ITSN1_HUMAN (75-640): 4.07e-22: 104: 13.88
+	Hs
		148770 MYO9B_HUMAN (43-823): 2.74e-75: 281: 13.14		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		1051315 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		DCTN1_HUMAN (88-572): 2.4e-12: 72.7: 10.41
+	Hs
		1133693 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		MY18A_HUMAN (329-637): 1.72e-11: 70: 17.67
+	Hs
		1133672 RHG21_HUMAN (88-1152): 8.55e-69: 260: 14.84		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		70674 MYO9A_HUMAN (346-832): 3.49e-66: 252: 20.35		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		1119951 RHG29_HUMAN (134-911): 5.44e-66: 249: 11.78		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		725200 RHG24_HUMAN (335-879): 3.02e-68: 248: 17.37		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79
+	Hs
		63075 RHG42_HUMAN (68-873): 1.41e-64: 240: 13.55		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		1068712 3BP1_HUMAN (368-686): 4.12e-64: 235: 25.94		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		968142 OCRL_HUMAN (86-552): 4.57e-62: 233: 14.14		PLEC_HUMAN (327-659): 1.61e-09: 63.5: 20.77
+	Hs
		725140 OCRL_HUMAN (86-552): 4.57e-62: 233: 14.14		MYH10_HUMAN (321-640): 8.77e-09: 61.2: 18.79