HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: EXO1 (Q9UQ84)
Exonuclease 1 (hExo1) (EC 3.1.-.-) (Exonuclease I) (hExoI)
Gene: EXO1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.50	0.632

Property	Details
Experiments	25833945, 35271311, 36931259, 22222486
Identification Methods	affinity chromatography technology, proximity labelling technology, two hybrid, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 846
+	Hs
		910169 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		927667 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		683822 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		684402 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		982630 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		905269 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		EXO1_HUMAN (1-846): 0: 1208: 100.00
+	Hs
		764357 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		FEN1_HUMAN (1-365): 6e-128: 390: 25.93
+	Hs
		982056 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		GEN_HUMAN (1-338): 5.74e-91: 309: 16.77
+	Hs
		904621 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		GEN_HUMAN (1-338): 5.74e-91: 309: 16.77
+	At
		965323 14332_ARATH (3-243): 8.65e-144: 404: 61.22		UVH3_ARATH (1-109): 3.08e-32: 137: 23.85