HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: KCC2A (Q9UQM7)
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CaM kinase II subunit alpha) (CaMK-II subunit alpha) (EC 2.7.11.17)
Gene: CAMK2A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	18292392
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 478
+	Hs
		910174 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KCC2A_HUMAN (1-478): 0: 565: 100.00
+	Mm
		515221 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KCC2A_MOUSE (1-478): 0: 566: 99.79
+	Hs
		909532 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KCC2D_HUMAN (2-476): 0: 552: 87.37
+	Hs
		683826 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KCC2A_HUMAN (1-478): 0: 565: 100.00
+	Mm
		926819 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KCC2D_MOUSE (2-476): 0: 552: 87.37
+	Mm
		926866 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KCC2G_MOUSE (1-476): 0: 524: 76.47
+	Mm
		659446 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		KCC2B_MOUSE (1-476): 6.17e-179: 514: 71.11
+	Hs
		684406 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		KCC2A_HUMAN (1-478): 0: 565: 100.00
+	Hs
		684020 1433S_HUMAN (1-236): 9.86e-108: 312: 71.85		KCC2D_HUMAN (2-476): 0: 552: 87.37
+	Hs
		904532 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		KCC2D_HUMAN (2-476): 0: 552: 87.37
+	At
		965291 14332_ARATH (3-243): 8.65e-144: 404: 61.22		CDPK1_ARATH (5-406): 1.98e-148: 438: 29.34
+	At
		802001 14334_ARATH (3-243): 2.7e-141: 398: 61.63		CDPK1_ARATH (5-406): 1.98e-148: 438: 29.34
+	Hs
		159186 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		CSKP_HUMAN (9-307): 2.92e-85: 282: 46.08
+	Hs
		683325 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KCC2B_HUMAN (218-475): 1.27e-60: 211: 42.44
+	Hs
		909531 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		KCC2G_HUMAN (276-475): 3.97e-45: 167: 53.50
+	Hs
		927014 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		KCC2G_HUMAN (276-475): 3.97e-45: 167: 53.50
+	Hs
		683326 1433B_HUMAN (1-242): 5.01e-139: 391: 81.82		KCC2G_HUMAN (276-475): 3.97e-45: 167: 53.50
+	Hs
		981988 1433F_HUMAN (2-242): 7.16e-106: 307: 71.43		KCC2G_HUMAN (276-475): 3.97e-45: 167: 53.50
+	Hs
		904531 1433G_HUMAN (1-242): 5.48e-105: 305: 70.33		KCC2G_HUMAN (276-475): 3.97e-45: 167: 53.50