HitPredict

Interactor 1: RHG32 (A7KAX9)
Rho GTPase-activating protein 32 (Brain-specific Rho GTPase-activating protein) (GAB-associated Cdc42/Rac GTPase-activating protein) (GC-GAP) (GTPase regulator interacting with TrkA) (Rho-type GTPase-activating protein 32) (Rho/Cdc42/Rac GTPase-activating protein RICS) (RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling) (p200RhoGAP) (p250GAP)
Gene: ARHGAP32

Interactor 2: RHOJ (Q9H4E5)
Rho-related GTP-binding protein RhoJ (Ras-like protein family member 7B) (Tc10-like GTP-binding protein)
Gene: RHOJ

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2087 Hs			1 214
+	Hs
		64680 RHG32_HUMAN (1-2087): 0: 1424: 100.00		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Mm
		892730 RHG32_MOUSE (1-2087): 0: 1404: 87.28		CDC42_MOUSE (20-204): 2.24e-92: 270: 63.78
+	Hs
		64688 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		64681 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RHOA_HUMAN (23-214): 1.09e-80: 240: 47.92
+	Hs
		64644 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RHOC_HUMAN (23-214): 6.63e-79: 236: 48.44
+	Hs
		64649 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RAC2_HUMAN (22-214): 1.98e-78: 235: 57.51
+	Hs
		64692 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RHOG_HUMAN (20-214): 1.44e-78: 235: 50.26
+	Hs
		64652 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RHOQ_HUMAN (22-213): 5.09e-77: 231: 79.49
+	Hs
		64679 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RAC3_HUMAN (22-195): 2.97e-77: 231: 62.64
+	Hs
		64686 RHG32_HUMAN (1-2087): 0: 1424: 100.00		RHOB_HUMAN (23-214): 1.69e-76: 230: 48.44
+	Mm
		925803 RHG32_MOUSE (1-2087): 0: 1404: 87.28		RAC1_MOUSE (22-214): 4.7e-82: 243: 57.51
+	Mm
		892729 RHG33_MOUSE (73-1289): 3.48e-114: 398: 30.65		CDC42_MOUSE (20-204): 2.24e-92: 270: 63.78
+	Hs
		147862 RHG33_HUMAN (74-1276): 2.2e-113: 395: 30.98		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Mm
		1194500 RHG33_MOUSE (73-1289): 3.48e-114: 398: 30.65		RHOJ_MOUSE (1-214): 5e-80: 239: 92.99
+	Dm
		776916 CDGAP_DROME (76-1527): 1.83e-93: 339: 20.94		RAC1_DROME (22-214): 1.4e-79: 237: 58.03
+	Hs
		894068 RHG44_HUMAN (335-893): 3.16e-80: 286: 19.37		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		893974 MYO9B_HUMAN (43-823): 2.74e-75: 281: 13.14		CDC42_HUMAN (20-204): 2.24e-92: 270: 63.78
+	Hs
		925314 RHG44_HUMAN (335-893): 3.16e-80: 286: 19.37		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		200213 SRGP3_HUMAN (294-939): 5.72e-78: 284: 17.36		RAC1_HUMAN (22-214): 4.7e-82: 243: 57.51
+	Hs
		436289 MYO9B_HUMAN (43-823): 2.74e-75: 281: 13.14		RHOC_HUMAN (23-214): 6.63e-79: 236: 48.44