HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: HECD4 (Q9Y4D8)
Probable E3 ubiquitin-protein ligase HECTD4 (EC 2.3.2.26) (HECT domain-containing protein 4) (HECT-type E3 ubiquitin transferase HECTD4)
Gene: HECTD4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 3996
+	Hs
		101681 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		F8VWT9_HUMAN (1-3996): 0: 7767: 99.03
+	Hs
		101690 1433Z_HUMAN (1-245): 1.75e-141: 397: 79.59		F8VWT9_HUMAN (1-3996): 0: 7767: 99.03
+	Hs
		125318 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		WWP2_HUMAN (3351-3991): 2.41e-145: 479: 16.52
+	Hs
		125169 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		WWP2_HUMAN (3351-3991): 2.41e-145: 479: 16.52
+	Mm
		808343 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NEDD4_MOUSE (3553-3991): 6.15e-141: 467: 18.86
+	Rn
		910358 1433E_RAT (2-243): 1.31e-144: 406: 63.53		NEDD4_RAT (3388-3991): 7.09e-140: 464: 16.04
+	Mm
		93264 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		E9PXB7_MOUSE (3482-3991): 2.05e-140: 464: 17.97
+	Hs
		808077 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NEDD4_HUMAN (3553-3991): 4.33e-135: 463: 18.86
+	Hs
		909930 1433E_HUMAN (2-243): 1.31e-144: 406: 63.53		NED4L_HUMAN (3482-3991): 2.77e-138: 462: 17.77
+	Mm
		910302 1433E_MOUSE (2-243): 1.31e-144: 406: 63.53		NED4L_MOUSE (3482-3991): 5.13e-138: 462: 17.97
+	Hs
		647267 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		WWP1_HUMAN (3457-3991): 7.23e-141: 468: 17.98
+	Hs
		647191 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		ITCH_HUMAN (3457-3991): 1.65e-140: 466: 18.22
+	Hs
		646713 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NEDD4_HUMAN (3553-3991): 4.33e-135: 463: 18.86
+	Mm
		93266 1433T_MOUSE (1-245): 2.96e-141: 397: 99.59		E9PXB7_MOUSE (3482-3991): 2.05e-140: 464: 17.97
+	Rn
		933150 1433T_RAT (1-245): 2.96e-141: 397: 99.59		NEDD4_RAT (3388-3991): 7.09e-140: 464: 16.04
+	Hs
		647201 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		NED4L_HUMAN (3482-3991): 2.77e-138: 462: 17.77
+	At
		788566 14333_ARATH (3-243): 8e-143: 401: 61.63		UPL2_ARATH (3535-3994): 3.29e-128: 458: 20.22
+	Hs
		647296 1433T_HUMAN (1-245): 9.47e-142: 398: 100.00		SMUF1_HUMAN (3571-3990): 3.67e-140: 460: 20.71
+	Mm
		926792 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		HERC2_MOUSE (3554-3989): 1.73e-110: 400: 27.07
+	Mm
		926831 1433Z_MOUSE (1-245): 3.06e-142: 399: 80.00		Q80W01_MOUSE (3698-3996): 8.21e-125: 397: 95.99