HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: IRS2 (Q9Y4H2)
Insulin receptor substrate 2 (IRS-2)
Gene: IRS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 0.60 0.718

The method score is based on:

Property Details
Experiments 17353931, 33961781, 36931259, 15161933, 28514442
Identification Methods affinity chromatography technology, proximity labelling technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0019904 - protein domain specific binding
GO:0071889 - 14-3-3 protein binding
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 245
Hs

1 1338
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024